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When is the Best Time to Take Nattokinase?

11/21/2017

79 Comments

 
Health supplement capsules resting on a green leaf

​When taking any kind of supplement or medication, it is important to know how and when to take it. This can be an especially important question when asking about nattokinase, because nattokinase is classified as a systemic enzyme, which means it works throughout the body, or "system", to build and maintain overall health. 


In order for a n​attokinase supplement to effectively find its way into the system, it needs to pass through the acidic environment of the stomach in a reasonable amount of time. With this being said, the best time to take nattokinase is on an empty stomach, and preferably with at least 8 ounces of water....
An encapsulated supplement can take anywhere from 15-45 minutes to make its way through the stomach, depending on the individual person. If there is food in the stomach, it can inhibit the pass-through process, and the acidity can even begin to break down the enzymes, minimizing the ability of the nattokinase to assimilate into the body and provide maximum benefit. So, what is considered to be an empty stomach? Arthur Andrew Medical, a leading enzyme supplement brand, suggests at least one hour prior to eating and/or two hours after eating a meal. It should also be noted that it is okay to take nattokinase with coffee, juices, tea, and other supplements.
​

Nattokinase Dosage

Nattovena Nattokinase available at Southwest NutraceuticalsAdvertisement
How much nattokinase to take depends on several factors such as the user's age, health, and a few other factors. An individual that is looking to take a nattokinase supplement for general health and prevention will most certainly take a lower dosage than someone that has a more serious existing condition. Be sure to follow the guidelines on a product label, especially if it states a maximum dosage, if you are unsure. 

At this time there is not enough scientific information to determine an appropriate range of doses for nattokinase, so keep in mind that natural products are not always necessarily safe, and understanding the proper dosages can be important. Once again, be sure to follow
 relevant directions on product labels, and consult your pharmacist, physician or other healthcare professional prior to using.​

Sources:
https://www.webmd.com
https://www.arthurandrew.com/media/Nattokinase_Clinical_Data.pdf
​https://www.globalhealingcenter.com/natural-health/difference-systemic-enzymes-digestive-enzymes/


79 Comments
Bruce Winter
11/1/2019 09:56:22 pm

I've been taking natto miso for years with supplements after the 1st meal. Now I'm seeing advice to take nattokinase on an empty stomach. Yes, it's a food and not a capsule so I'm wondering if I'm negating the benefits of the enzyme not taking it in non-food form. I just turned 80 and the low BP and blood work always draws comments.

Reply
John link
11/2/2019 08:59:00 am

Hi Bruce...you are still getting the benefits of natto, but in supplement form, nattokinase products are optimal when taken away from food (30-45 minutes before a meal, or 2 hours after a meal). This allows the enzymes to enter the body without being "distracted" by food nutrients.

Digestive enzyme supplements, which are meant to assist the body in the breakdown of foods, can and should be taken with a meal.

Reply
JJ
9/7/2020 11:33:26 am

I have been taking nattokinase 2000FU 2-3X/day on empty stomach for a DVT in lower leg... with very good results... much less swelling and pain in only a week. I refused taking Eliquis or Warfarin, after a ton of reading... much to my Doctor's anger.

Is it safe to add Lumbrokinase to the mix... or should I alternate every few weeks? I don't want blood to be overwhelmed, but need the dissolving action to be as strong as is reasonably safe.

I am also taking 80000SPU Serrapeptase 2X/day and applying topical 50%+ DMSO to leg 2X/day.

I'm very positive about this... knock on wood! Thx!

Reply
John link
9/10/2020 11:08:14 am

Hi JJ,
I think that taking both together will be expensive and redundant. If anything, maybe switch off every few weeks or a month at a time. This will also help you determine if one of them is providing a greater benefit to you. All the best!

Reply
JJ
9/10/2020 11:13:31 am

I think you mean taking Nattokinase and Lumbrokinase together... and agree... but I read that taking teh Natto-k and Serrapeptase apart but same day is fine... they seem to do some slightly different things and some similar things... with a DVT, I need anti-coagulation, and the Nattokinase and lumbrokinase I think are much better for that then the serrapeptase... but the Serra works great for the associated inflammation and pain, now much reduced...
Agree?

John link
9/10/2020 11:32:02 am

Yes, I was referring to the lumbrokinase and nattokinase together. Serrapeptase is a fantastic enzyme to be supplementing for pain and inflammation issues. Great for breaking down fibrous tissues.

Reply
JJ
9/10/2020 11:41:31 am

Got it... any dosage recommendations? think the serrapeptase really needs to be enteric coated?

How about topical DMSO (and magnesium oil) on the bad leg? I think it would be very beneficial, was doing it from the start 10 days ago... lots of claims that it works on clots, especially ischemic strokes... but it may have contributed to what I think was a Herxheimer reaction... I am also considering drinking a small amount of DMSO with juice... but with the enzymes... might be a little much...

BTW: I appreciate your feedback!

Lisa Samuelsen
3/16/2021 07:20:02 am

I am currently taking Lumbrokinase (20mg) first thing in the morning, on an empty stomach. I am now going to be adding Nattokinase (100 mg) to my routine at night, also on an empty stomach. When researching how these supplements should be taken, I read Lumbrokinase is best in morning and Nattokinase us best at night. I don't know if taking both in the same day is over kill or not, but they both seem to have very good benefits and can work on different things.

John link
9/10/2020 12:43:39 pm

Hi JJ,

To be honest, I am not entirely familiar with the effects of DMSO, so you may want to give it a good trial run and see if it provides you any benefit.

As far as a dosage (and this goes for any product really), I can't recommend a dosage that is beyond what is recommended on the bottle. When it comes to enzymes, your body is going to use what it needs and then flush the rest.

It has been shown that serrapeptase does not need to be "enteric coated." We actually sell a form of serrapeptase that is not and it is highly effective. The product is called Serretia, from Arthur Andrew Medical, and it uses a proprietary encapsulation that acts like an enteric coating, but made with cellulose (the main component of veggie caps). You can read more about it here:
https://www.swnutra.com/blog/acid-armor-vs-enteric-coating

Hope that helps!

Reply
JJ
9/10/2020 01:03:30 pm

Yes, The DMSO was of benefit... I just worry about it accentuating the effects/power of the nattokinase or lumbrokinase...
DMSO is said ti be a strong clot-buster in its own right.

The acid stuff was interesting... thx!

Reply
JJ
9/10/2020 04:51:06 pm

Hi, John, another question... I read that 1-2 glasses of red wine help thin the blood and help prevent clot formation.
Sounds great, I love the stuff... I until recently drank a glass of red wine with lunch... 6-8oz only.
think it would interact/reduce effectiveness of nattokinase?
thx!

Reply
John link
9/11/2020 09:26:59 am

Alcohol in general will thin blood, but as long as it is used in moderation, it should not have much of an effect, if any, with the effectiveness of a nattokinase supplement.

JJ
9/11/2020 09:59:51 am

That is great news... I really enjoyed my small glass of red with lunch...

I found what seems to be a good Naturopathic Doctor (NMD) he spent 40 minutes with me to sort of get to know each other before committing... think a regular Doc would? Jeeze. He knows about nattokinase, etc... so might be a good fit.

BTW: I just found out my sensitive estradiol was really low, 8.5... but a friend said that Lab Corp sensitive estradiol is known to be wildly inaccurate... jeeze again! I'll be re-tested soon, regular not sensitive, but the red wine is supposed to mildly up the estrogen... YAY!

Brian Moala
3/9/2021 07:50:38 am

Can you take Nattokinase and Horse Chestnut extract together

Reply
JJ
3/9/2021 08:39:25 am

I am not very familiar with Horse Chestnut, but since it seems to have blood thinning properties, I would not take with nattokinase... which also has blood thinning properties... depending on what you are trying to solve, I would consider lumbrokinase instead... I have not posted here for a while, but I switched to the Boluoke brand of lumbrokinase on the recommendation of my NMD, and with serrapeptase, it defeated my DVT (blood clot) in a bit more than 3 months... FAR better than warfarin or Eliquis would have done, without the risk.
BTW: If choosing only between horse chestnut and nattokinase, I would take the nattokinase... buy the NK-SD form, it is far superior.

Reply
Kat Andrews link
3/15/2021 09:59:56 pm

I have been taking Nato Kinase for 2 years now, I have been taking 2000 FU + K2 MK-7with Natokinase 100mcg and I just started to take Heal -n- SOOTHE byLiving well can you look at this product online and the ingrediants it's a systemic enzyme blend but I am worried about the product I take the Nato at bedtime and the heal and soothe 2 in the am and one more in the afternoon. But I am wondering if together with the Nato is it safe because the Heal & soothe has got also blood thinning properties in it. I had auto accident in 2018 and have had pain ever since. So that is why I am taking the the Heal & soothe. Today is the 2nd day on it and it already is helping. can you e-mail me back. Thanks so much Kat

Reply
JJ
3/16/2021 08:29:15 am

Hi, Kat, I think the only thing in your heal n soothe that thins blood is ginger. IMO, that stuff is WAY overpriced... I recommend buying Devil's claw and bromelain individually ( I use Swansons or Ebay)... and adding 40-80,000 spu serrapeptase to that mix, empty stomach... then you save a ton... get a stronger dose of both the DC and Brom, and don't get the ginger... and add a great anti-inflammatory and healer in serrapeptase.
Avoid aspirin too. Ibuprophen should be OK... only if you really need it.
I am not a MD, so just my opinions. Hope they help!

Reply
Michael
5/15/2021 03:37:36 am

I have a family history of heart disease and a coronary calcium scan show some build up on the left side. My blood pressure is also high. I’ve been working on my diet and fasting for 18 hours daily. Around 16 hours into the fast I take 8,000 fu of Nattokinase in hopes that it will help my arteries. Is there any negative to taking this in a fasted state?

Reply
JJ
5/15/2021 07:14:52 am

I am not a Doctor... but... IMO...I think Nattokinase is supposed to be taken on an empty stomach, otherwise it becomes an expensive digestive enzyme... fasting means empty stomach, so no problem.
I would recommend adding at least 40,000SPU of Serrapeptase to your daily protocol...
IF you are taking ANY sort of blood thinners, prescription or otherwise (aspirin, turmeric, ginger, etc)... check with your doctor, though most traditional MDs don't know squat about enzymes or most non-Big Pharma treatments... I have a good naturopathic MD (NMD), really helps.

Reply
Glenn
9/9/2021 09:15:25 am

Thanks for all of your helpful comments. Can you tell me who your naturopath is? I want to clear my arteries but am confused by how much of what to take etc. Thanks

Bruce winter
9/9/2021 12:58:26 pm

Glenn, I don't have a naturopath I do my own research. I take natto miso which was in supermarkets in Hawaii. Now a friend ships me a box every few months. No problem being room temp for a few days. Or probably longer.

JJ
9/9/2021 01:12:38 pm

Sure, Glenn... again, I am not a doctor, so this is not medical advice... but it depends, IMO, on the amount of clogging you currently have in your arteries... your Cardiologist should be able to do tests to tell you that... for MY blood clot/DVT... I took up to two 20mg Lumbrokinase (Blouoke brand) three time/day... and 80,000 SPU of Serrapeptase daily... always on empty stomach... and waited 30-60 minutes after before eating. That was for a serious, even life threatening condition... for maintenance now, I take one 20mg lumbrokinase (either Boluoke or Doctors Best brand) twice a day... and 40,000-80,000 SPU Serrapeptase daily... it is important, IMO to buy enteric coated products.
I have not taken either natto or nattokinase, as the above mix worked so well for me.
As an aside... I am hoping these enzymes also will mitigate the damage that the Covid "vaccines" afflict the bodies of the poor vaxxed can do... I am not vaxxed, but the vaxxed shed the spike proteins, so it is still a concern.
GL to you!

glenn
9/10/2021 05:48:22 am

hi j.j. thanks for your reply - in your above post you said you have a good naturopath m.d. i was wondering if i could have his/her name & contact info. many thanks

JJ
9/10/2021 08:52:07 am

Oops! His name is Dr. Jorge Cochran NMD in Tucson, 520-546-3233 he now works with a NP that can prescribe drugs that he cannot. GL to you!

Susan
6/7/2021 06:46:24 am

Good day.
I take 100mg Nattokinase and 80,000 of Serapeptase on empty stomach.
I also take Qucertin, ubiniquol and digestive enzymes and the usual multi cal/mag D, B complex.
Is this ok to take on daily basis or am I just wasting my money with some.
Eg: when reading about Nattokinase it seems to also have alot of vitamins and minerals in it plus protein?.
Do i need multivitamins etc too ?
I would hate to be taking unnecessary supplements.

Thank you.
Susan.


Reply
JJ
6/7/2021 07:00:44 am

Hello, Susan,
I think 100mg Nattokinase daily is a good maintenance dosage, though I prefer Lumbrokinase, as I have had a DVT previously and Lumbrokinase is a much stronger "clot dissolver/preventative"
I sometimes take 40,000 Serrapeptase, sometimes 80,000, usually only 40,000.
I do not think nattokinase has enough vitamins or protein to preclude you taking a multi. I would NOT recommend supplementing calcium, but taking at least 5,000iu of D3 daily... your multi should contain enough B-complex. Most good multis require 2-3 pills daily, taken at different times (meals?). I recommend extra magnesium and boron.
Quercetin is a good supplement, but gives me side effects. Ubiquinol is great, especially if you take a statin drug. I prefer taking Bergamot extract to a statin. Digestive enzymes are fine.
All this just my non-MD opinion!

Reply
Michelle Kauler
8/1/2021 05:23:10 pm

Is it ok to take Nattokinase as we as olive leaf extract?

Reply
JJ
8/1/2021 06:12:14 pm

I am no Doc... but I doubt they would interact... BUT... I recommend not taking them at the same time... all such enzymes as nattokinase should be taken on an empty stomach... alone.

Don't waste the enzymatic action on the Olive Leaf extract. Allow it to work on the BAD stuff!

Reply
Bradley
8/2/2021 04:15:23 pm

What JJ said is good advice...There aren't any known interactions between the two, but always best to take enzyme supplements (unless it's a digestive enzyme supplement) away from foods and other such dietary products. Doing this will increase the efficiency and absorption of both the nattokinase and the olive leaf extract. All the best!

Reply
Vera Osborn
8/9/2021 01:32:52 pm

I suffered a stroke in 2017. I've been on several BP medicines, none of which helped, just made my pressure go very low and caused me dizziness and I was unable to function. I got off of them and now taking Hawthorne berry. But, I need something else to manage my pressure. It goes up to 175/64, and I that's not good. Can take Nattokinaise? I'm 85 yrs old and generally very healthy.

Reply
JJ
8/9/2021 01:52:03 pm

I am not a doctor... keep that in mind... I would assume you are on blood thinners... so nattokinase may not be a great fit... or serrapeptase... if NOT on blood thinners, they IMO, would be helpful. I think lumbrokinase might do you a lot of good... it supposedly doesn't have the bleeding risk that the others do...
My father was helped a lot by going on an old style BP med... Hytrin... I'd start a 1 mg and ramp up slowly after monitoring your BP closely. You may well have been given too strong of a dose of the others... that is common.
If your pipes are clogged (have them checked if you have not already)... serrapeptase is great, but again. careful if you are on blood thinners...
BTW: Are you scared of having your BP taken now? I am, and often get high readings like yours when in a Doc's office or am anxious... but when at home and relaxed... totally normal, even a little lower... take yours at home with a wrist cuff... often... btw: That 64 diastolic is great! Again, do your homework, I am NOT an MD!

Reply
Vera Osborn
8/9/2021 04:36:47 pm

I am not on blood thinners. My doctor put me HCTZ 12.5mg and Simvastatin 20mg. That made my pressure after a time, very low. I stayed on Simvastatin for my Cholesterol. I was then put on Losartan 50mg/ HCTZ 12.5mg. At first it worked very well, my BP was consistent for a while. Then it started going very low, and I was having the same problem again. So I stopped taking anything, except Hawthorn Blend. I don't feel dizzy but sometimes I feel lightheaded. But that doesn't normalize my BP. I know I should take something because I get a pain in the left side of my head below my ear. It comes and goes. My Blood workup has been very good. I have to keep my pressure under control because I have high pressure in my eye, for which I use eyedrops. (Cataracts removed) I know you are not a doctor, but can you just tell me, can I possibly benefit from Nattokinaise?

Zan
1/31/2023 09:36:26 am

There are people who took Olive leaf extract 750mg 2 to 3 times a day and it kept their bp under control

Reply
JJ
8/9/2021 04:54:09 pm

The Hydrochlorothiazide (HCTZ) could cause low BP, if you got to a point that you did not need a diuretic anymore... was your use monitored closely?
The Simvastatin should not have had a major effect either way on your BP... it is a cholesterol med... a Statin, not a BP med.
I would ask your Doc about starting low dose Lisinopril or Hytrin, as I mentioned before... especially if you have consistently high BP... Nattokinase is great, but IMO, will not solve your BP issues in the short or mid-term... it is great for unclogging the veins and arteries over time, which will effect BP positively... I would add in Serrapeptase, which dose similar things, but is a great inflammation reducer and plaque remover... over time...
For now, I would get on low-dose Lisinopril or Hytrin... if the first one gives you problems, switch, but under the supervision of your cardiologist... beginning on low dose should not give you the bad side effects or too low BP... meanwhile, the Nattokinase/Serrapeptase can be working on cleaning your "pipes".
All just my non-medical opinions!! Unfortunately, most "mainstream" MDs know nothing of enzymes like Nattokinase or serrapeptase.

Reply
jan gridley
10/1/2021 08:13:51 pm

My husband had a ischemic stroke recently. He took a prescription blood thinner for 90 days along with aspirin. Now that he's off blood thinner & aspirin, we are trying nattokinaise. 1 in a.m & 2 bedtime. Problem is he refuses to give up his 6 oz. Of milk at bedtime. Will that negate the natto's effectiveness.

Reply
JJ
10/1/2021 08:34:30 pm

Hmmmmm... again, I am NOT a doctor, so do your own research... but... I am surprised that your husband was taken off blood thinners after only 90 days... I would HOPE that was due to them confirming his blood clot was completely gone? Perhaps his stroke was "provoked" and the risk is now gone? Unlikely...
Still I would have thought they would keep him on low dose something for a lot longer than 3 months...
The main thing about Nattokinase or the other enzymes is that they need to be taken on an empty stomach... so simply tell him to work around the Nattokinase and the milk... I'd prefer waiting an hour (30 minutes at least) after the Nattokinase dose before eating (or drinking anything but water, coffee or tea)... and two hours AFTER eating/drinking anything is when to take the Nattokinase.
I think Nattokinase would be fine... and effective... but I prefer taking lumbrokinase and serrapeptase instead... Lumbrokinase is a far stronger clot (fibrin) dissolver than nattokinase... but either way should be effective.
If he (and you) are vaxxed... the clotting risk rises significantly, from all that I have read... so taking either the nattokinase or a prescription blood thinner might be even more important... is it possible the stroke was a vaxx side effect?

Reply
jan gridley
1/10/2022 03:45:15 pm

No, he's not vaxxed, doesn't intend to. What brand of lumbrokinase do you recommend?

JJ
1/10/2022 04:34:01 pm

I took Boluoke brand Lumbrokinase, but I think Dr's Best is probably just fine, and much less.
I use Serra-Rx brand serrapeptase... Dr's Best might even be better...

Good for him on refusing the clot-shot!

Lakhwinder
11/8/2021 08:38:45 pm

Can u take nattokianse and probiotic together before go to bed.

Reply
Bradley
11/9/2021 02:18:45 pm

Prior to bedtime is a good time to take supplements like these because they are generally recommended to be taken away from food. I am not aware of any interactions between the two.

Reply
JJ
11/9/2021 02:39:16 pm

Nattokinase needs to be taken on an empty stomach... I don't know about combining with probiotics, but I wouldn't...

I think 30 minutes min before or after.... JMHO

Reply
RK
5/17/2022 12:20:14 pm

I have a hard time swallowing capsules. Can I open up the nattokinase and mix it into some liquid and take it that way?

Thank You!

John link
5/23/2022 02:30:15 pm

Hi RK,

The short answer to your question is yes, you can pull apart the capsules if you have a hard time swallowing them. However, there are two things to note when doing this.

It won't taste good at all. I recommend adding the contents to a flavored beverage or yogurt to help disguise the taste.

Second, anytime that you open up the capsules, you are going to be taking away from the effectiveness and absorbability of the product. The capsules help to protect the contents from the digestive process so that as many of the enzymes can get to where they need to go in the body. People do this all the time though...these are just some things to be aware of. Hope that helps and makes sense.

Best of luck!

Deedee
11/28/2021 08:19:08 am

What is the big difference between lumbrokinase and nattokinase? Every time I have been vaccinated my d dimer goes up which is terrifying. Is this due to the spike protein and what is that relationship to clotting? The rest of my blood tests are ok, and I actually git a CT scan after the 1st vaccine and all was fine. It does cause great anxiety and eventually, it does resolve itself. Trying to figure out how much nattikonase to take and if U should switch to lumbrokinase. Earth worms?? I also take 1-3 g of fish oil and curcumin. Both are said to help to thin blood. I have high BP and noticed to recommend lisinopril. Why lisnopril? Why Hytrin? The side effects from BP meds have horrific. Got tachy cardia from htz because can’t keep hydrated because any liquid I drink is quickly removed. I and this vaccine also has its issues. Trying to balance it all out.

Reply
JJ
11/28/2021 09:16:06 am

I am NOT a Doctor... but have done a lot of reading on these enzymes...
I used Lumbrokinase (Boluoke brand) to defeat a serious DVT in 3 months, and took no Eliquis or warfarin (my doctors all went bananas)... do your own research... what I have found might not fit YOUR situation... I think nattokinase is a great every day supplement for many things... I have been on lumbrokinase (LK) daily since my DVT in 9/20, but might switch to Nattokinase (NK) as my DVT was likely "provoked" by testosterone replacement therapy... I do have, supposedly, Leiden V, a clotting disorder, so this is serious stuff for me... I have been also taking Serrapeptase with the Lumbrokinase daily, 40000 to 80000 daily. Personally, I would not combine LK with NK... but would take serrapeptase with either. I think NK benefits more overall than LK, but LK is MUCH stronger in terms of dissolving fibrin/blood clots...
Yes, I would for sure be concerned about the "vaccines" causing blood clotting... VERY concerned... perhaps a combo of LK and Serrapeptase would be appropriate for you, a Naturopathic MD knowledgeable about these enzymes would be a worthy investment. I would not take aspirin with NK. From online articles:

The most unique feature of NK is that, as a single compound, it possesses multiple CVD preventative and alleviating pharmacologic effects (namely, antithrombotic, antihypertensive, anticoagulant, anti-atherosclerotic, and neuroprotective effects). There are no other drugs or drug candidates with multiple pharmacologic properties similar to NK.Of all the proteolytic, or protein digesting enzymes, only serrapeptase and nattokinase come close to resembling lumbrokinase in terms of fibrinolytic activity.

However, lumbrokinase is “king” when it comes to strength, as it’s:

About 300-times stronger than serrapeptase, an enzyme extracted from silkworms.
Nearly 30-times stronger than nattokinase, the notorious enzyme extracted from natto, or traditional Japanese fermented soybeans.

Reply
Kristine
12/20/2021 07:25:43 pm

"Personally, I would not combine LK with NK... but would take serrapeptase with either."

I have seen people take LK with NK and am just wondering what your reasons are for not wanting to combine these two together?

Thanks

Reply
JJ
12/20/2021 08:51:37 pm

Remember, I am no Doc...

I think taking both might be overkill... I prefer lumbrokinase as it's :

"About 300-times stronger than serrapeptase, an enzyme extracted from silkworms.
Nearly 30-times stronger than nattokinase, the notorious enzyme extracted from natto, or traditional Japanese fermented soybeans.

Here’s something else that makes lumbrokinase stand apart from the others...

It has a built-in balancing mechanism that promotes both fibrinolysis and fibrinogenesis. That means it can both break down and build up fibrin, depending upon your body’s needs..."

Nattokinase, to my knowledge, does not have this balancing mechanism... so could cause too much blood thinning... for example, nattokinase and aspirin are not recommended together... and nattokinase has to be stopped well before any surgery...

I take serrapeptase too, for inflammation control and to keep my pipes clear... it eats arterial plaque. I take them at different times... some don't bother.

Reply
Kristine
12/21/2021 08:07:10 pm

Okay good points, thanks.

I was thinking of taking LK am, Serrapeptase in afternoon and NK at night.

That way, covering all bases as they are all just a bit different and may have different helpful mechanisms.

I agree though that LK is the winner of them all, if I had to limit to one.

Thanks

Reply
Jay
1/9/2022 07:27:00 am

Started 100mg NK. I noticed that the multi/v I’m taking has high E in it. 67mg of d alpha tocopherol succinate. Any cause for concern, or just lower the dosage of the synthetic E ?

Reply
Maurits de vries
2/11/2022 03:05:03 am

I take one Natto capsule everymorning on a empty stomach, and right after that I take one glass of Diatomaceous earth. Now I`m wondering can the particles in the Diatomaceous earth harm the enzymes? or is that not possible?

Reply
JJ
2/11/2022 08:42:29 am

I think taking the DE right after the natto (you meant nattokinase?) capsule would completely negate any benefit... IMO, the DE would absorb the nattokinase or prevent its absorption. IF you really mean natto, not nattokinase, that would be even more likely to be rendered useless.

I recommend taking them at least an hour apart, both on empty stomach, better yet, take at different times of day. I take DE before bed.

JMHO

Reply
Maurits de vries
2/11/2022 01:17:05 pm

Thank you for your comments

I mean indeed natto kinaso supplements and not natto

Debbie Gonzalez
2/16/2022 09:08:19 pm

Hi there,
I am hoping you might be able to tell me if taking 60,000 total FU (of a combo) nattokinase and serrepeptase is okay to do (2 in morning 2 later in afternoon) along with a 325mg asprin?

The reason I took the asprin, this evening, was because I felt my hand starting to be tingly; this prompted me to do the asprin for microblood clot concerns....

I believe I am suffering my 5th round of covid... I am unvaxed.

Thank you for your thoughts!

Reply
RT
2/25/2022 06:51:52 pm

i have enjoyed everyone's honest opinion and sharing of their medical condition me personally i had a lung embolism blood clotting and had some clots removed but after 6 months of taking Eliquis 5mg 2x a day they have not dissolved the clots and the problem with the medical community they are trained to give you a prescription that may or may not work and more importantly cause you more harm so now i am on my own quest to find solutions to my own condition and it has been helpful in hearing from you all even though we are not doctors we can at least give our honest opinions and i sincerely thank you all especially you JJ because you let me see that i am on the right track.

Reply
JJ
2/26/2022 08:40:23 am

My pleasure, RT, I am glad you are going in the right direction. It is sad that Cardiologists do not recommend Lumbrokinase along with drugs like Eliquis (which do nothing to dissolve a clot)... but... if they keep your clot in place, very slowly dissolving... they make far more PROFIT.

I wish you well...

Reply
T.S.
3/27/2022 12:59:57 pm

I'm old. (83) In my past I've had BOTH corotid arteries surgically scrapped out. Both ops were a success. I have no complaint concerning the surgeon nor the ops themselves. I've also had one heart attack resulting in a stent. (not medicated) I used to smoke and as a result Mr. Emphysema knows my name. But that was then and back then I knew NOTHING of serrapeptase nor nattokinase. If I did I would have taken steps to prevent a reoccurrence. However, I am showing symptoms from ALL 3 areas telling me the crud is back. At my age I am NOT a good surgical risk. (Not that I would.) Here's my plan of action: (Due to my schedule I can only carve out 2 "time windows.") When I wake: 250,000 IU serrapeptase and 2000 FU nattokinase. I repeat the procedure every 12 hours thereafter. If anyone has any suggestions toward a better plan I'm all ears. Thank you.

Reply
JJ
3/27/2022 01:25:27 pm

You plan seems sound... personally, I would exchange nattokinase for lumbrokinase... the strong dosage of both serrapeptase and nattokinase might thin the blood (anticoagulant anti platelet action) a bit too much... and lumbrokinase is many times stronger than nattokinase. I recommend no aspirin if you stick with your plan and don't switch.
I would also recommend, for overall health improvement, researching Dr. Kalcker's work with Chlorine Dioxide Solution (CDS)... on Bitchute, not the censorship monster and Big Pharma shill Youtube... I do not recommend MMS at all. Both demonized, but that is likely due to Big Pharma worrying about their profits. I have taken for a month+ and it has helped a lot, and no side effects.
GL to you and blah blah, this is not medical advice. ;-)

Reply
Russ
4/3/2022 08:45:01 am

I was recently diagnosed with Afib and have had one additional episode over a 5 month period of time. Prior to this I did have a brain stroke 14 years ago. I am now 75. I was maintained an Plavix following the stroke with no side effects. After the Afib diagnosis I was told to stop the Plavix and prescribed Eliquis. I could not tolerate Eliquis with many side effects. In the meantime, after talking with my local pharmacist, he suggested I try a quality Nattokinase (DaVinci Labs). I take one 150 mg a day with absolutely no side effects.

Now, my cardiologist is recommending I take Xeralto. I have taken Xeralto in the past due to a blood clot in my leg and the bleeding side effects were significant.

I know you are not a doctor as I am just looking for another opinion.

My question is this: considering the recent diagnosis of Afib, and the Nattokinase I now take, should I also take the Xeralto and just tolerate the bleeding side effects (bleeding when brushing teeth, blood under skin on arms)? Taking both ok?

Reply
JJ
4/3/2022 11:54:55 am

Well... unfortunately Afib is really tough to treat naturally... beyond any expertise I may have... I will say though... that nattokinase and serrapeptase, especially together, like in your DaVinci supplement (a good one, IMO) can cause blood thinning... when combined with a prescription blood thinner/anticoagulant,,, it might be too much... I worry about a hemorrhagic stroke... make darn sure your MD (and pharmacist) knows about you taking them together... I bet he says NO.
Look into lumbrokinase, it does not have the potential bleeding side effects that nattokinase and serrapeptase have, serrapeptase much less that nattokinase... and may help you to knock out mini-clots if they form.
I really dislike prescription blood thinners, especially Eliquis, but all are nasty drugs... with Afib, though... your options are so limited... perhaps your MD will reduce the dosage of Xarelto if he is OK with you taking your DaVinci supplement... IF you can handle a strict diet... warfarin may be a better option with less side effects... BTW: Dabigatran or Pradaxa get far better reviews than Xarelto, which gets worse reviews than even Eliquis...
Get your exercise, move to a strongly anti-inflammatory diet, avoid aspirin... they say Yoga helps (jeeze!)... I sure wish you well...

Reply
Lark
8/9/2022 08:23:02 am

Wow! First I’m glad I found you. Long post. Had atrial tachycardia for about 17 years treated successfully with flecinide. (I think it was a result of fosamax). Had a heart attack in 8/20. Stent in LAD. Treated with statin (which I stopped) and Brilinta with low dose aspirin. Stopped those about 11 months later. Got Covid on 11/2/21 had second heart attack on 11/17/21. Treated in ER with TNKase. Was given Brilinta with aspirin, entresto (switched to Losartin, farxiga, statin. Awful side effects. I’ve stopped all except Brilinta and aspirin. Doctor and NP would not listen. Brought in all of my supplements, D-Ribose, CoQ10, nattokinase, cholesterol complete, Mag, taurine, etc., neither one of them would even look at the bottles. Had LOTS I’d palpitations, which I told them about repeatedly. Wire the Zio. They saw everything (SVTs and one AFib) and referred me to EP for discussion of ablation. He is changing my meds from Brilinta to Eliquis due to the one AFib episode (feel like it’s a death sentence). Have not started E. Recommended another ECHO before moving forward. Not jabbed. See an acupuncturist, DC, and reflexologist routinely. Just did a liver/gallbladder cleanse. (They thought I had hepatitis and sent me for an ultrasound and discovered the gallstones, which, of course, can only be resolved with surgery. Please advise! Thank you. Thank you.

Reply
JJ
8/9/2022 11:11:15 am

I wish I could be of help to you... you have a lot going on, and my level of expertise is simply not adequate to advise you... you need a great cardiologist and a great naturopathic MD (NMD), probably also consult with a vascular surgeon and lipid specialist.

I am a big fan of the enzymes discussed here... and also a substance called Chlorine Dioxide Solution (CDS) Look up a video by Dr. kalcker, the foremost expert on CDS called "CDS for newbies". Interesting!! It may solve a lot of problems... but do your homework and consult with good people!!

Reply
JFit link
9/6/2022 10:26:04 pm

Hello JJ, I read your comments on Nattokinase, Lumbrokinase, and Serrapeptase. I've been in the healthcare field for some 27 years with a specialty in clinical exercise physiology and functional integrative medicine. I am very familiar with proteolytic enzymes but I have personally not tried them up until a month ago. I was on TRT and one other prescription drug called Tadalafil. I was taking both and turned out the Tadalafil was a mistake. I had a low blood flow stroke due to taking the 5mg daily Tadalafil. Had the stroke in April 2022 and it basically effected coordination on my right side. I'm about 90% back to normal, but it was scary for sure. The concluded it was the Tadalafil because every major artery and blood vessel was clean as a whistle. 0% plaque according to the scans. My heart is perfect and I had a neural scan done last month and the docs said my brain was performing better than the average healthy adult so I am very grateful. Anyways, after the stroke I stopped the TRT cold turkey and of course stopped the Tadalafil. All my clotting factors and everything else related to clotting and inflammation came back completely normal. My BP averages 110/70 and sometimes in the mornings it would be as low as 95/60 and this is why I was not a good candidate for taking a vasodilator because when I stood up from my desk after sitting for 90 minutes that morning, I stroked out immediately. Horrible! On the day of my stroke my hemoglobin was 15.9 and my hematocrit was 48% so docs didn't think anything of it. I've always been a little concerned about elevated hematocrit, but with exercise and hydration it helps keep things flowing. I was just curious if you knew what your hematorcrit numbers were when you were diagnosed with your blood clots? Have you noticed any difference in decreased hematocrit since taking the lumbrokinase/serrapeptase. I have all 3 and been taking nattokinase religiously the past few weeks and I am doing blood work tomorrow. Was just curious if you have seen it lower hematocrit? Oh, I never got vaxxed either because something deep down told me to not do it. Yes, I got ridiculed for it and had to do telemedicine from home, but so glad I didn't follow the rest of my colleagues because now there is a lot of talk about funeral directors and embalmers finding strange strands of clots in people so much so that they are unable to drain the blood without getting backflow into their systems. I've also had friends who have serious side effects from the vax. One was perfectly healthy and had a stroke 2 weeks after his second shot. BTW, I am 58 years of age with ZERO underlying medical issues and I just started back on TRT last week. Injecting 15mg daily since that dose before was getting my total T up in the 1100 range and free T in the mid 200s. Thanks for any feedback!

JJ
9/8/2022 11:44:33 am

I think your Doc made a mistake giving you the Tadalafil if your BP was low-normal... consider consulting an attorney... I tried that drug and it gave me many issues too... very rapid heart rate... scary... anxiety, brain fog...
Be careful with nattokinase, it caused MY BP to go too low... 90/52... which is why I went back to Lumbrokinase... plus, I have histamine intolerance and MCAS, and nattokinase is usually from a fermented source...
My hematocrit was normal before my DVT... it wasn't checked after... I did find out I had Leiden V, which the Docs should have tested for prior, but I find these days most Docs are Big Pharma stooges and are there to prescribe their poisons, not to really diagnose and treat anymore... TRT can provoke a clot in several ways, raising hematocrit is just one...
Lumbrokinase should reduce hematocrit, but if yours is normal... might not be much difference...
Yes, I didn't take the death-jab either, lucky to be into alternative news sources... most MSM is still pushing the jabs, even though the numbers of people dead and disabled is growing fast and is already appalling... it WILL get worse... clotting and dementia are slow to get to the levels of major problems... we are entering that time-frame now...
Glad you are doing much better... I would still be wary of TRT...

Reply
Mena mary baldeosingh
11/28/2022 12:43:37 am

Hi I just saw these comments here and I wish I can get some info on taking. NATTOKINASE. CAN WE CONTACT BY MAIL? Thank you so much.

Reply
Spurzo
12/4/2022 04:39:57 am

What’s the effective dose of Nattokinase to dissolve block clots and fibrin?

Right now I’m taking 2000 fu in the morning. I also take 4 g fish oil, 2400 mg garlic extract, 200 IU Vitamin E, 240 mg ginkgo biloba per day away from nattokinase . And I also take 81 mg aspirin at night.

Reply
JJ
12/4/2022 08:23:49 am

First, I am no Doctor... but IMO... if you know you have a clot, Lumbrokinase is 30X stronger in dissolving clots/fibrin than nattokinase. IF you do not... then nattokinase 2000FU is a good preventive for clots and vascular health.
I would check in with a naturopath, if you are able... as IMO, you are taking in a LOT of blood thinning supplements daily... perhaps too many. You CAN get too much of a good thing... and increase your risk of a hemorrhagic stroke or other bleeding problem...

Reply
Amanda Bullock
1/1/2023 10:28:39 pm

Wow what an informative site! So glad I found it.
Currently on 10 mg xarelto for a DVT in left leg. I had to ask for a lower dose from dr and am determined to get off them completely. Currently taking Nattokinase in am empty stomach and 60000 serrapeptase daily. After reading thru these comments I might switch out the natto for the lumbrokinase.
I also take quercetin, vitamin d, methyl, resveratrol, ginkgo biloba, a multivitamin, glutathione, burdock root, and NAC- does this all seem like too much? Thanks so much!

Reply
JJ
1/2/2023 02:21:15 pm

Again, I am not a MD and do not offer any advice... but for only myself... I wonder, did you tell your doctors about all the stuff you are taking? Seems to be a LOT, considering you have added several blood thinners on top of the anti-coagulant. Do you have a CURRENT DVT?? Where is it located?
Lumbrokinase is 30X stronger in dissolving clots than nattokinase, and has less effect on coagulation, some say none. Serrapeptase does thin blood, but much less than nattokinase. I hope you are not taking aspirin with all that stuff...
I admit, I am not a fan of MDs these days, most are Big Pharma tools. Maybe find yourself a good naturopathic MD (NMD), even if you have to tele-conference.
You might ask if staying on low-dose Xarelto for a while, and adding lumbrokinase (I used Boluoke, but Drs Best may be OK for much less... though if I had a current DVT, I would spend the big bucks)... maybe keep the serrapeptase for pain, inflammation and a few extra benefits...
But remember... you need to consult with a pro... who has experience with enzymes... I have only my own research and experience with my DVT, which was one leg, just above the knee to the ankle... far less of a threat than a DVT that is much higher up... Remember, I used topical 70/30 99.995% pure DMSO gel on my leg too... I think that helped, perhaps a lot. GL to you!

Reply
Amanda Bullock
1/2/2023 02:44:45 pm

Thanks for your comments JJ. Yes I do have a kickass naturopath ever since I got my DVT last March. It was most likely from the vaxx due to timing and no other logical reason drs could find. I am despising drs and big pharma right now as well which is why I am doing a lot of research on natural methods to dissolve and keep the clots away. My DVT was lower leg and was quite long. I will request another ultrasound this March at 1 year to see if it is still present. If it is gone I will likely request to be off xarelto and move to just enzyme and supplement maintenance.
Thanks again for the site and the answers you provide to everyone!

Lucy
1/11/2023 06:44:20 am

I want to to Nattokinase on a long term basis for all of its benefits but mainly because of its ability to attack the spike protein in acute covid. When I take it on an empty stomach I get migraines so it benefits me much more to take capsules with food but now I fear I’m wasting its potential. Please note I’m not too bothered about taking it for blood clotting issues even though I do have a post-viral chronic illness that came along before covid

Reply
JJ
1/11/2023 08:00:04 am

Yes, IMO, taking nattokinase with food pretty much turns it into a digestive enzyme and cancels out most or all of its intended benefits. I don't take nattokinase because it gives me some side effects, probably because it comes from fermented substance... and I have histamine intolerance issues... perhaps you do too.
Also, Lumbrokinase is far more powerful than nattokinase, so you might want to give it a try... I have not had any problems with it, and always take on an empty stomach. I take serrapeptase too, same way, no problems.
For that post-viral illness, I would look into Ivermectin, D3 and Zinc.
Keep in mind, I am not a Doc and do not offer medical advice. GL!! ;-)

Reply
LINDA M STEWART link
1/15/2023 03:39:57 pm

I was taking Lumbrokinse for high LP(a). It did lower my numbers but not to within the normal range. I just had a calcium scoring done on my heart and scored a zero. I just switched to Nattokinase by Orthomolecular Products. Not sure if it will help. I did notice in the thread that said not to take Nattokinase with a calcium supplement. I do have osteopenia so I think I need a calcium supplement. Thanks so much.
Linda

Reply
JJ
1/15/2023 04:07:37 pm

Hi, Linda... I know it is boring, but remember, I am not a Doc and do not offer medical advice... but if it were me, I'd congratulate myself on that zero Calcium CT score!! (Mine was zero last time too, so I did!)... I would take 2-3 grams of liposomal vitamin C daily, in split doses and take Lysine with each dose. Also a couple of cups of coffee, if you tolerate it well, carnatine, vitamin e (mixed tocopherols and tocotrienols) and a good EPA fish oil supplement. Also I suggest a low carb diet.

With your zero Cal CT score, I would not get too nervous... especially if your LDL score is normal... and I think enzyme supplements will go a long way to avoid the increased clotting risk that lipo(a) brings... though I have not read that clotting risk is a big factor in elevated lipo(a)... I prefer Lumbrokinase and serrapeptase, but if you prefer nattokinase... OK.
I would not take calcium for osteopenia, in fact, IMO, it is dangerous... though many MDs recommend it... ( I am not a big fan of most MDs)... I think taking vitamin K2(Mk7) and D3 is a far better idea.

This sure is getting to be a long thread!! I hope some others will jump in and give their opinions and responses to questions... ;-)

Reply
Rachel Bettenson
1/17/2023 02:01:18 am

Very impressed with the info on this site. I'm looking for help for my 32 yr old son who had the shot and now has blood clots near his heart and constant left side pain. Not much for specialists and doctors in our isolated area so I'm looking for info on helping him naturally.

Reply
JJ
1/17/2023 08:44:23 am

Very sorry to hear... how did you find out he had clots near the heart and what doctor told you this... and what did they recommend/prescribe? If clots near the heart were found, I would have thought your son would (should) be in a hospital...
I recommend contacting a good Naturopathic Doctor, you can do tele-appointments... if you do not have one locally, you might do a consultation with Dr. Jerry Taylor in MT... (406) 265-2250. I believe he is knowledgeable about enzymes, not sure if he recommends one of MY favorites, chlorine dioxide solution (CDS).
If this was me... (not medical advice), Ivermectin, lumbrokinase, serrapeptase, CDS, EPA fish oil, quercetin or rutin, l-citrulline, magnesium glycinate... possibly internal DMSO... but consulting a doctor for this serious situation is a must. GL to you both!

Reply
Elaine HORTON-BENNETT
1/19/2023 06:24:10 pm

WOW...LOVING THIS THREAD! So much knowledge and experience. I have worked in Natural Health field for many years. I have become a follower of Anthony Williams who is followed by millions. I have adopted some of his protocols and recommendations with great improvements. I have developed a DVT to the left of mt knee...with discolouration circuling my knee. I have tried high dose Serrapeptase (250iu) with some success with surrounding vein inflammation. I have been on 2 x 2000fu Nattokinase caps at bedtime for 5 days with an improvement. Based on all IMO advice...going to swop Nattokinese for Lumberkinese because of my DVT. So my question is (finally) A. Williams (aka Medical Medium) highly recommends NOT taking any fish oils (filled with heavy metals even those claimed to be 'CLEAN' and to obtain Omega three from Algae. Any thoughts please?

Reply
Yoke Wong
1/30/2023 08:29:15 pm

Is it safe to eat Nattokinese while I am also on statin to lower cholesterol? Thank you.

Reply
JJ
1/31/2023 12:01:31 pm

I am not a Doc and do not offer medical advice... but if it were me, I would ask for a C-reactive protein and Lipo(a) test before taking any statin... unless my total and LDL numbers were above 250+ and 130+ respectively... even then, if my C-rp and Lipo(a) numbers were normal... I'd try to solve via diet changes and taking Bergamot, EPA fish oil, plant sterols, maybe guggul.
IF I was really concerned, I would request a cardiac Calcium CT scan, fine out if your coronary arteries are clogging up.
I know of no interaction between statins and nattokinase, but ask a naturopath... regular MDs usually know zero about enzymes.
IF I were ever to take a statin, it would be 5mg Crestor generic (rosuvastatin) and get re-checked in a few months. AND take Co-Q10 with it.
IMO, cholesterol problems are related to INFLAMMATION, far more than cholesterol levels... unless those levels are very high. That is indicated in the C-RP blood test. Some like the Homocysteine test too.

Reply
JJ
1/31/2023 12:04:13 pm

Sorry... inflammation is indicated by the C-RP and homocysteine tests, cholesterol levels are indicated by the usual tests.

I was not clear and there is no EDIT button!




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